ByDr. Brennan Commerford, Chiropractic Physician·Last reviewed: April 2026
All Ingredients
Specialty1 form

Luteolin

Preferred Form
Extract
Bioavailability
S2
Evidence Level
Moderate Evidence

Quick Answer

What is the best form of Luteolin?

Extract is our top-ranked form of Luteolin, classified as T1 Preferred with S2 bioavailability. We compared 1 forms in our formulary.

Our recommendation: Extract

1forms compared

All Forms of Luteolin

FormTierBioavailabilityDose RangeUnit
ExtractT1 PreferredS2

Bioavailability by Form

S2 — Good
Extract

What is Luteolin?

Luteolin is a Specialty supplement available in 1 form.

Not all forms of Luteolin are equal. The form you choose determines how much Luteolin actually reaches your tissues, and the difference between the best and worst forms can be substantial. This standardized luteolin extract provides the bioflavonoid compound with well-characterized anti-inflammatory and mast cell-stabilizing activity. Research suggests luteolin supports healthy histamine response, NF-kB regulation, and cognitive function by modulating inflammatory signaling pathways.

Forms of Luteolin Compared

Luteolin Preferred (T1 Preferred) has a bioavailability rating of good (S2). Typical dose range: not yet documented in our database.

What the Research Shows

Luteolin is a flavonoid with potent mast cell stabilizing and neuroprotective properties. Research demonstrates it inhibits neuroinflammatory pathways and supports blood-brain barrier integrity. Clinical interest is growing for its role in neurological health, with studies showing effects on microglial activation and inflammatory cytokine modulation.

How to Choose the Right Form

Luteolin is classified as T1 Preferred in the FormulaForge formulary — our top recommendation for Luteolin. It carries a bioavailability rating of good (S2), meaning more of the active compound reaches your tissues per dose unit compared to lower-tier forms.

When choosing a Luteolin supplement, look for the S1 (best absorption) bioavailability tier on the label or formulary listing. T1 Preferred forms have the strongest research-backed evidence for efficient absorption.

Other forms may be appropriate depending on individual goals, cost considerations, and your healthcare provider’s guidance. The best form for you depends on your specific health needs.

Dosing & Safety

For Luteolin, the typical dosing range is not yet documented in our database. Individual dose requirements vary based on health goals, body weight, and existing nutrient intake.

Side Effects: Specific side effect data for these forms is not yet documented in our database. In general, consult your healthcare provider regarding tolerability at higher doses.

These statements are based on structure/function research and have not been evaluated by the FDA. This information is not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider before starting or changing a supplement regimen.

Dosing Guidance

Dosing information not yet available for this ingredient.

Frequently Asked Questions

What is the best form of Luteolin?
Luteolin is the T1 Preferred form of Luteolin in the FormulaForge formulary, reflecting research-backed evidence for superior bioavailability (good (S2)). This classification is based on published absorption studies and clinical evidence quality. The best form for you depends on your individual health goals and your healthcare provider's recommendations. Always consult a qualified healthcare provider before starting, stopping, or adjusting any supplement regimen.
How much Luteolin should I take daily?
Dosing information for Luteolin is being compiled in our database. Individual dose requirements vary based on health goals and existing nutrient intake. Always consult a qualified healthcare provider before starting, stopping, or adjusting any supplement regimen. These statements are based on structure/function research and have not been evaluated by the FDA. This information is not intended to diagnose, treat, cure, or prevent any disease.
What are the benefits of Luteolin?
Luteolin has been studied for its role in supporting: Supports healthy inflammatory response via mast cell stabilization, Supports neurological health and neuroprotection, Supports cellular health and healthy aging, Supports antioxidant defense. Luteolin is a flavonoid with potent mast cell stabilizing and neuroprotective properties. Research demonstrates it inhibits neuroinflammatory pathways and supports blood-brain barrier integrity. Clinical interest is growing for its role in neurological health, with studies showing effects on microglial activation and inflammatory cytokine modulation. These statements are based on structure/function research and have not been evaluated by the FDA. This information is not intended to diagnose, treat, cure, or prevent any disease.
When is the best time to take Luteolin?
Optimal timing for Luteolin supplementation depends on the specific form, dosage, and individual factors. Some forms may be better absorbed with food; others may not require food. Always consult a qualified healthcare provider before starting, stopping, or adjusting any supplement regimen.
Are there side effects of taking Luteolin?
Tolerability of this Specialty supplement varies by individual, dose, and specific form. Some individuals may experience gastrointestinal discomfort at higher doses. Specific side effect profiles for each form of Luteolin are documented in our formulary where available. Always consult a qualified healthcare provider before starting, stopping, or adjusting any supplement regimen. These statements are based on structure/function research and have not been evaluated by the FDA. This information is not intended to diagnose, treat, cure, or prevent any disease.
What forms of Luteolin are available?
There are 1 form of Luteolin in our formulary: Luteolin (T1 Preferred, bioavailability: good (S2)). Forms differ in chemical structure, bioavailability, and typical dose range. FormulaForge classifies forms by tier based on published bioavailability evidence.

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FormulaForge formulates and sells supplements containing the ingredients discussed on this page. Our formulary recommendations are based on peer-reviewed bioavailability research. All cited studies are independently verifiable.