ByDr. Brennan Commerford, D.C.·Last reviewed: May 2026
All Ingredients
Botanical1 form

Licorice Root Extract

Preferred Form
Glycyrrhizic Acid 20%
Absorption Score
64/100Very Good
Evidence Level
Moderate Evidence

See all Licorice Root Extract forms ranked

Scored by absorption, bioavailability & formulary tier

View scores

Quick Answer

What is the best form of Licorice Root Extract?

Glycyrrhizic Acid 20% is our top-rated form of Licorice Root Extract — the form we recommend for its High Absorption bioavailability. We compared 1 forms in our formulary.

✓ Top Pick: Glycyrrhizic Acid 20%

1forms compared

All Forms of Licorice Root Extract

FormTierAbsorption ScoreDose RangeUnit
Glycyrrhizic Acid 20%Preferred
64/100Very Good

Absorption by Form

Very Good
Glycyrrhizic Acid 20%
64/100

What is Licorice Root Extract?

Licorice Root Extract is a Botanical supplement available in 1 form.

Not all forms of Licorice Root Extract are equal. The form you choose determines how much Licorice Root Extract actually reaches your tissues, and the difference between the best and worst forms can be substantial. Licorice root extract standardized to 20% glycyrrhizic acid provides consistent potency of the primary saponin that supports healthy cortisol metabolism and mucosal integrity. Research suggests this standardized form promotes healthy adrenal function and gastrointestinal mucosal health with predictable glycyrrhizinic acid delivery.

Forms of Licorice Root Extract Compared

Licorice (Glycyrrhiza glabra) Root Extract (20% Glycyrrhizic Acid) Preferred (Preferred Form) has a bioavailability rating of good (S2). Typical dose range: not yet documented in our database.

What the Research Shows

Licorice root extract standardized to 20% glycyrrhizic acid provides the bioactive triterpene saponin responsible for adrenal and digestive support. Research demonstrates cortisol-sparing effects via 11-beta-HSD2 enzyme inhibition. Note: prolonged high-dose use requires monitoring due to potential mineralocorticoid effects on blood pressure and potassium levels.

How to Choose the Right Form

Licorice (Glycyrrhiza glabra) Root Extract (20% Glycyrrhizic Acid) is classified as Preferred Form by FormulaForge — our top recommendation for Licorice Root Extract. It carries a bioavailability rating of good (S2), meaning more of the active compound reaches your tissues per dose unit compared to lower-rated forms.

When choosing a Licorice Root Extract supplement, look for the S1 (best absorption) bioavailability tier on the label. Preferred Forms have the strongest research-backed evidence for efficient absorption.

Other forms may be appropriate depending on individual goals, cost considerations, and your healthcare provider’s guidance. The best form for you depends on your specific health needs.

Dosing & Safety

For Licorice (Glycyrrhiza glabra) Root Extract (20% Glycyrrhizic Acid), the typical dosing range is not yet documented in our database. Individual dose requirements vary based on health goals, body weight, and existing nutrient intake.

Side Effects: Specific side effect data for these forms is not yet documented in our database. In general, consult your healthcare provider regarding tolerability at higher doses.

These statements are based on structure/function research and have not been evaluated by the FDA. This information is not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider before starting or changing a supplement regimen.

Dosing Guidance

Dosing information not yet available for this ingredient.

Frequently Asked Questions

What is the best form of Licorice Root Extract?
Our top-ranked form of Licorice Root Extract is Glycyrrhizic Acid 20%. It has High Absorption bioavailability, meaning your body absorbs and uses it efficiently. When choosing Licorice Root Extract supplements, prioritize this form over generic alternatives.
How much Licorice Root Extract should I take?
Dosing for Licorice Root Extract varies based on the specific form, your health goals, and individual factors. Consult a qualified healthcare provider for personalized guidance.
What does Licorice Root Extract support?
Licorice Root Extract is commonly used to support Botanical. Research suggests it plays a role in several physiological pathways. As with all supplements, these statements have not been evaluated by the FDA and Licorice Root Extract is not intended to diagnose, treat, cure, or prevent any disease.
Is Licorice Root Extract safe?
Licorice Root Extract is generally well-tolerated when taken at research-supported doses. As with any supplement, individual responses vary. Consult a qualified healthcare provider before use, especially if you are pregnant, nursing, have a medical condition, or take medications. These statements have not been evaluated by the FDA.

Ready to formulate with Licorice Root Extract?

Our formulary recommends Glycyrrhizic Acid 20% for optimal bioavailability. Build your personalized formula now.

Start My Formula

Compare & Learn More

FormulaForge formulates and sells supplements containing the ingredients discussed on this page. Our formulary recommendations are based on peer-reviewed bioavailability research. All cited studies are independently verifiable.