Indole-3-Carbinol (I3C)

Indole-3-Carbinol (I3C) is a Specialty supplement available in 1 form.

Not all forms of Indole-3-Carbinol (I3C) are equal. The form you choose determines how much Indole-3-Carbinol (I3C) actually reaches your tissues, and the difference between the best and worst forms can be substantial. Indole-3-carbinol (I3C) is the natural cruciferous vegetable compound that converts to DIM and other acid condensation products in the stomach, providing a broader spectrum of indole metabolites than DIM alone. Research supports I3C for promoting healthy estrogen metabolism, Nrf2 pathway activation, and cellular health.

Indole-3-Carbinol (I3C) (Secondary Form) has a bioavailability rating of good (S2). Typical dose range: not yet documented in our database.

Indole-3-Carbinol (I3C) is a glucosinolate breakdown product from cruciferous vegetables that supports Phase I estrogen metabolism. In the stomach, I3C converts to DIM and other metabolites. Research supports I3C for estrogen balance, with studies demonstrating shifts toward favorable 2-hydroxy estrogen metabolites. It complements DIM supplementation by providing upstream pathway support.

Multiple forms of Indole-3-Carbinol (I3C) are available. Start by comparing form ratings — Preferred Forms reflect the strongest bioavailability evidence, and S1-rated forms deliver the most active compound per dose unit.

The appropriate form depends on your individual goals and your healthcare provider’s recommendations. Consult a qualified professional before selecting a supplement form.

For Indole-3-Carbinol (I3C), the typical dosing range is not yet documented in our database. Individual dose requirements vary based on health goals, body weight, and existing nutrient intake.

Side Effects: Specific side effect data for these forms is not yet documented in our database. In general, consult your healthcare provider regarding tolerability at higher doses.

These statements are based on structure/function research and have not been evaluated by the FDA. This information is not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider before starting or changing a supplement regimen.