Supplement Form Comparisons

5x absorption advantage with significantly fewer GI side effects at therapeutic doses.

The only curcumin form with clinical evidence for crossing the blood-brain barrier.

Free fatty acid form delivers measurably higher EPA/DHA uptake than ethyl ester concentrates.

Spore-forming strains survive stomach acid intact — standard lactobacillus strains largely do not.

Only ~40% of adults can convert pomegranate polyphenols to urolithin A — the active mitophagy trigger.

Pea sprout extract targets follicle signaling pathways; biotin only corrects deficiency-driven loss.

Micronized particle size dramatically improves dissolution and mitochondrial uptake kinetics.

Standardized whole coffee fruit concentrate with consistent BDNF-elevating polyphenol fractions.

Nattokinase has the stronger human clinical trial record for healthy fibrinolytic activity.

No published evidence supports superiority of HCl over monohydrate. 500+ studies back the original form.

Creapure is creatine monohydrate — the same molecule with German-verified purity. Purity vs price.

D3 raises serum 25(OH)D levels ~15.69 nmol/L higher than D2 at equivalent doses in meta-analysis data.

KSM-66 has the largest RCT database of any ashwagandha form, standardized to 5% withanolides root-only.

Sensoril uses whole-plant extraction at 10% withanolides; KSM-66 uses root-only at 5%.

Shoden has 35% withanolide glycosides — the highest concentration of any standardized ashwagandha extract.

The 40:1 myo:DCI ratio mirrors human follicular fluid — high-dose DCI alone is counterproductive.

Over 80% absorption for glycinate vs ~4% for oxide — a 20x gap that makes oxide ineffective.

Glycinate offers superior absorption (>80%) and no laxative effect; citrate is cheaper with mild bowel benefit.

Threonate crosses the blood-brain barrier for cognitive support; glycinate is optimal for systemic replenishment.

Ubiquinol absorbs 3.5x better and requires no conversion — especially important for adults over 40.

TG form achieves 124% relative bioavailability vs 73% for ethyl ester in head-to-head research.

Krill oil's phospholipid omega-3 has preferential brain uptake and includes choline; fish oil offers higher EPA/DHA per capsule.